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Behavioral medicine approaches, particularly Biofeedback, relaxation training, as well as cognitive-behavioral techniques have been identified as efficacious treatments for headache, both for adults and children [17 25].
Therefore, drugs originally identified as efficacious in one disease could potentially be of therapeutic benefit in another.
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From this series of compounds, compound 17a was identified as an efficacious, safe, and selective inhibitor of DPP-4.
Of the four drugs identified as most efficacious in this meta-analysis, sertraline and escitalopram were better tolerated than mirtazapine and venlafaxine [ 30].
Most people identify as straight.
With this rationale, the test arm with the highest observed response rate was to be identified as the most efficacious test arm.
ACR20 results for other dose groups are shown in figure 2A, with the 100 mg q2w dose identified as a non-efficacious treatment group.
Antibodies that target the envelope glycoproteins, including diverse sequences within the first and second hypervariable regions (V1V2) of gp120, were identified as correlates of risk for the one partially efficacious HIV-1 vaccine.
Depression has been identified as the single most important factor predictive of efficacious Spinal Cord Stimulation [33], and other factors including somatization, anxiety, poor coping also predict poor response [34].
Development of accurate and efficacious methods of diagnosis and treatment has been identified as a research priority.
BMS-189664 (3) is identified as a potent, selective, and orally active reversible inhibitor of human α-thrombin which is efficacious in vivo in a mouse lethality model, and at inhibiting both arterial and venous thrombosis in cynomolgus monkey models.
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