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These genes were however not identified as acquired by any of the methods used.
In addition, most of the genes identified as acquired through HGT in a genome have not been fixed in the population, and most of them never will be.
Whether a gene could be identified as acquired through HGT would depend on how divergent the source species was and whether its sequences were available; therefore, painstaking investigation of each gene would only result in eliminating some, but not all, such genes.
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Strengths of this study include the large cohort of patients identified as acquiring MRSA during admission to a tertiary hospital.
Of these, 212 (72.9%) were acquired MDRTB cases, and 79 (27.1%) were unambiguously identified as initially MDR.
There were no ISs close to other genes identified as potentially acquired by HGT (Table 2).
Average BMI was 23.16 ± 3.82 and 37.7% were identified as hospital acquired infections.
We assumed that also patients not tested with AI but identified as recently acquired infections with the other criteria have an AI < 0.80.
Recently, new evidences recommended that infants who were seropositive for HBsAg and HBV DNA at 7 months could be identified as having acquired HBV infection [ 6- 9].
A PiggyBac element identified as recently acquired in bats has been demonstrated to retain activity when inserted into both human and yeast cells, highlighting the capacity of this particular family of transposons for inter-species transfer [ 76].
Among them, RGENs are the latest gene knockout tools that were originally identified as an acquired immunity-like system in bacteria to protect the host from invading viruses or plasmids (Wiedenheft et al. 2012; Mali et al. 2013).
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