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Additionally, the fast mode peaks that have previously been labeled as the kinetically hot residues are identified as a second folding core set dependent on local interactions.
Compound (1f) was identified as one of these hits with an IC50 of 89.5 μM for EeAChE and 153.8 μM for EqBuChE, (2a) was identified as a second hit with an IC50 of 108.4 μM (EeAChE) and 277.8 μM (EqBuChE).
In addition, thymidine phosphorylase (TYMP; previously known as endothelial cell growth factor 1, ECGF1) was identified as a second key astrocyte-derived permeability factor, which interacts with VEGFA to induce blood-brain barrier disruption [119].
The criterion that was to provide the line of demarcation between empirical statements and others was verifiability, a criterion which has been identified as a second "dogma" of empiricism.
The pro-inflammatory cytokine, interleukin 1 (IL1) was identified as a second putative modulator (p<0.0001) for the top network formed by genes with elevated synchrony in depression (Figure 3D; Table 1).
Recently, CXCR7 was identified as a second receptor for CXCL12.
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