Sentence examples for identified alteration in from inspiring English sources

These observations are intriguing given the high frequency of AKT signalling pathway activation in HGSC [ 77- 79], whereby the TCGA study identified alteration in the PI3K/AKT and RAS pathways in approximately 45% of HGSC [ 11].

Among the identified alteration in biological activities in OTSCC, the most significantly enhanced are related to the extracellular matrix remodeling (GO 0030574, GO 0030198), I-kappaB kinase/NF-kappaB cascade (GO 0043123) and chemotaxis (GO 0050921), which are known to be related to tumorgenesis and progression of the cancer.

Mapping altered metabolites to KEGG and SMPDB pathways identified alterations in immunomodulatory pathways including tryptophan catabolism and eicosanoid biosynthesis.

In the current study, we identified alterations in both systemic and cerebral hemodynamics.

Recently identified alterations in the function of specific genes in these cancers provide new potential therapeutic targets.

We identified alterations in DNA copy number and complex genomic rearrangements and demonstrated a low somatic point mutation frequency in the absence of tobacco mutagens.

In summary, molecular profiling of chRCC identified alterations in genes and protein expression that might provide a mechanistic rationale for off-label use of approved therapies in advanced chRCC, and could guide the design of molecularly targeted clinical trials.

As a result, we identified alterations in the expression of stathmin1.

Moreover, several studies have identified alterations in specific PP2A subunits in human cancers, which has led to the hypothesis that PP2A serves as a tumor suppressor [6], [7].

This study identified alterations in gene expression that occur in three strains of scrapie in mice.

Metabolite analysis of FH-deficient cysts and tumors identified alterations in urea cycle metabolism.