Exact(3)
The identified alignment is not necessarily optimal if there is a gap between the score and the upper bound.
GO enrichment measures the functional coherence of the proteins in an identified alignment with respect to the biological process annotation of GO, for each species separately.
While the Viterbi decoding assigns gain only if the whole alignment is correctly predicted, posterior decoding assigns gain +1 for each correctly identified alignment column.
Similar(57)
Instead, it continues reporting identified alignments until reaching the maximal limit of the number of alignments.
The Perl script to identify loci takes into account alignment score, coverage, and the number of identified alignments both between and within parents.
Bowtie2 by default performs a non-exhaustive search for distinct valid alignments, and then reports the single best result of the identified alignments.
To identify alignment and amplification artifacts, custom R scripts were used to analyze the aligned reads of all single-end libraries with more than 10 duplicates (defined as having the same chromosome, start and strand values).
The first stage of MUMmer alignment involves identifying alignment anchors.
This method allowed us to identify alignment blocks with TFBS turnover (gain or loss) while controlling the FDR at 10%.
At the end, we curated the final list manually to identify alignment artefacts of the mapping algorithm.
RAPSearch, however, requires a substantial memory footprint to identify alignment seeds, due to its use of a suffix array data structure.
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