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The best variants identified acquired up to 11 amino acid alterations.
F1174V is a recently identified acquired point mutation relating to the Crizotinib resistance in NSCLC patients.
Genome sequencing identified acquired mutations in several human tumor suppressor homologs.
Many patients with C3G have identified acquired or genetic defects associated with AP dysregulation [ 18].
MMS refers to a moyamoya angiopathy associated with other neurological and/or extra-neurological symptoms, or due to a well identified acquired (see Table 2) or inherited cause (see Table 3).
For example, a study by Fenger-Eriksen and colleagues identified acquired fibrinogen deficiency as the main determinant of the dilutional coagulopathy induced by hydroxyethyl starches in patients undergoing total cystectomy [ 43].
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Several interviewees identified acquiring the funding to survive the therapy development process as the single biggest challenge facing firms in the field.
The first identifies innate traits with those characteristic of an entire species and identifies acquired traits with those that vary between populations and individuals.
It is now affordable to sequence an entire prokaryotic genome in order to identify acquired mutations [2].
The genetic basis for phenotype alteration can be identified directly by sequencing the entire genome of the mutant and comparing it to the wild-type (WT) genome, thus identifying acquired mutations.
To determine whether or not SNP-A can be used as an accurate and effective method to identify acquired UPD, we studied patients with typical MPD homozygous for the V617F mutation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com