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From the 445 peptides examined manually, a further 11 sites were identified (a sensitivity of 88%) and 14 were assigned as negative, giving a selectivity of 85.1%.
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When detecting the M121I mutation, 42 of 42 mutant samples were identified, with a sensitivity of 100%, and 45 of 47 wild type samples were identified, with a specificity of 95.7%.
Using these criteria alone, ischemic limbs were identified to a sensitivity of 69% and specificity of 95%.
Lymph node metastases could be identified with a sensitivity of 65.5% at specificity of 98.7% by postoperative characteristics.
Lymph node metastases could be identified with a sensitivity of 55.2% at specificity of 93.7% by preoperative characteristics (Table 4).
Using an L/ T ratio of <2 to predict metastases, both benign and malignant nodes were correctly identified with a sensitivity of 95%.
Based on combination of preoperative characteristics and ZEB1 expression, lymph node metastases could be identified with a sensitivity of 62.1% at specificity of 96.2% prior to hysterectomy.
Furthermore, lymph node metastases could be identified with a sensitivity of 62.1% at specificity of 96.2% by combination of preoperative characteristics and ZEB1 expression.
Lymph node metastases could be identified with a sensitivity of 55.2% at specificity of 93.7% by preoperative characteristics from the pathological analysis of endometrial samples.
Based on the combination of preoperative characteristics and ZEB1 expression, lymph node metastases could be identified with a sensitivity of 62.1% at specificity of 96.2% (Table 4).
Lymph node metastases could be identified with a sensitivity of 57.8% at specificity of 74.1% by ZEB1 expression in endometrial biopsy.
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