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The next goal of this study was to determine if these 11 genes represented a generic response to proteinuria that was present in other forms of primary GN because our in vitro experiments identified a response of tubular cells to albumin that was independent of glomerular injury.
We have identified a response regulator (MtRR1, Mtr.43735.1.S1_at) that is up-regulated in the embryogenic cultures.
In an earlier study Oliver's group identified a response to altered growth rates that was common across nutritional conditions [ 7].
Jones et al. evaluated the steroidal AI exemestane in 91 patients and identified a response rate (complete response + partial response) of 13% [ 7].
An interim analysis of the first 40 patients [ 49] identified a response rate of approximately 30%, with a similar percentage of patients experiencing stable disease.
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Volker Turk, the UNHCR's assistant high commissioner for protection, said: "I see it as the beginning of an exciting process … it identifies a response framework that consolidates the nuts and bolts of what is needed if a country is faced with a large-scale [refugee] situation".
In the proposed approach, we first select the most informative voxels and then identify a response pattern based on the connectivity of the selected voxels.
The ITBV from the PiCCO demonstrates more clinical utility in identifying a response to FC.
Our previous studies of cellular stress responses in C. elegans identified a cellular response that is easily visualized in C. elegans intestinal cells [8], [9].
At this point, we identified a complete response on PET and fundoscopic examination, and then we changed his chemotherapy to capecitabine (1200 mg/body) alone.
Within this key promoter region we identified a metal response element pertaining to a putative Metal Transcription Factor-1 (MTF-1) binding site.
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