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Human genome scans have identified a locus responsible for controlling Schistosoma mansoni infection intensity on chromosome 5q31 q33.
For a third trait, cardiac troponin T, investigation of regulatory domains identified a locus on chromosome 9.
We recently identified a locus on chromosome 10p13 p12.1 involved in permanent neonatal diabetes mellitus associated with pancreatic and cerebellar agenesis in a genome-wide linkage search of a consanguineous Pakistani family3.
We also identified a locus associated with partial resistance on chromosome 12.
Huang et al. (2015) also identified a locus associated with blast resistance in the vicinity of Pi33 target zone.
We previously identified a locus on distal mouse chromosome 7 that contributes over 50% of the variation in postischemic cerebral infarct volume observed between inbred strains.
Here, using a CSSL population between Nipponbare and Kasalath, which show contrasted levels of NIS (Additional file 1: Figure S1 and S2), we identified a locus, called NIS1, on chromosome 1 (Figure 4A).
We have identified a locus on murine chromosome 2 at approximately 35.8 Mb that is strongly associated (LOD score = 9.0) with inflammatory responses in the absence of PECAM.
Furthermore, Lindemann et al. [30] identified a locus in strain SCHU S4 separate from the O-antigen locus [31] that is required for LPS O-antigen and/or capsule biosynthesis.
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