Sentence examples for identified a dose from inspiring English sources
To determine whether the effects of IL-6 on food intake are mTOR-dependent, we first identified a dose of Rapamycin that did not alter food intake (25 µg) when administered at the onset of the dark cycle.
Thus, to determine whether the effects of IL-6 on food intake are AMPK-dependent, we first identified a dose of AICAR that did not alter food intake (0.5 mM) when administered at the onset of the dark cycle.
To determine whether the effects of IL-6 on food intake are also JAK2/STAT3-dependent, we first identified a dose of AG490 that did not alter food intake when administered at the onset of the dark cycle.
Patients who identified a dose that produced satisfactory PR for at least two target breakthrough pain episodes were eligible to enter the double-blind crossover period.
This is the first report of the only Phase I experience combining the triple-drug regimen RVd with the monoclonal antibody Elo for newly diagnosed myeloma, and has identified a dose for further study.
The present study could not confirm a statistical association with the age of the patients, but identified a dose dependency of the effects, which did not occur in the study by Centorinno and co-workers.
In contrast, the dual-stain procedure identified a dose-dependent decrease in viability and increased necrozoospermia for CAM and GEN treatments.
Thus we have identified a dose-dependent rescue using an inhibitor that is specific to NICD production within the cytoplasm.
We assessed the biological gradient of smoke exposure in pregnancy and identified a dose-dependent response of methylation with both increased intensity and duration of smoking.
If a method of identifying patients who have a high risk of local failure could be identified, a dose-escalation regimen that allows a higher rate of treatment-associated toxicity may be seen as worthwhile.
Heller et al. [ 23] used Omegaven in a heterogeneous group of patients including post-surgical, septic and trauma patients and identified a dose-dependent reduction in mortality predicted from SAPS II score at entry.
