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Using the above statistical threshold, we identified a consensus of 853 DEGs upregulated in basal and 940 DEGs in luminal cells (Supplementary Data 1).
By applying a stringent statistic threshold of greater than equal to twofold change (FC) and false discovery rate (FDR) of <0.05, we identified a consensus of 853 differentially expressed genes (DEGs) upregulated in basal and 940 DEGs in luminal cells (Supplementary Data 1).
Based on the structure, we applied a recently developed method for epitope design that combines computational epitope predictions with in vitro mapping experiments and successfully identified a consensus sequence within the antigen that, when engineered as a synthetic peptide, was selectively immunorecognized to the same extent as the recombinant protein in sera from melioidosis-affected subjects.
Using flow cytometric analyses, we identified a consensus surface activation marker signature (SAMS), CD14+CD69+CD86+CD68lo on a subpopulation of MDM in which HIV replication was active [52].
Analysis of these validated regions identified a consensus DNA sequence (motif) that associated with 75% of the promoters.
Examination of the mouse proximal NTCP promoter region identified a consensus DBP binding site conserved in several mammalian species (Figure 7A).
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Also, it is recommended to model the decision making in a probabilistic framework rather than a deterministic "one score" approach, seek to identify a consensus ranking, place particular attention on determining the values of the criteria that emerged as "top" at the evaluation stage and continue to emphasize risk measures.
A bioinformatics tool (GLAM2) was used to identify a consensus sequence and an Environmental Induced Differential Methylation Consensus Sequence 1 (EDM1) motif was identified.
TBC has the advantage of a quadratic complexity, and there is the possibility to identify a consensus partition and a measure of cluster reliability.
Although there are multiple combinations for satisfying each representation goal, we were able to identify a consensus solution for each scenario in which total 'costs' were the smallest.
Current research efforts at WRAIR seek to identify a consensus AMA-1 molecule/chimera that would elicit a broad immunity active against multiple P. falciparum AMA-1 phenotypes [43].
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