Sentence examples for identification of toxicity from inspiring English sources

Although this was an animal study with limited samples, it validated the effectiveness of DNB for the identification of toxicity mechanisms and the early diagnosis of carbonyl chloride induced acute lung injury.

In addition, since no patient showed full recovery of eGFR, earlier identification of toxicity prior to development of renal function decline is important.

The benefits of such a system should include improved therapy (efficacy), reduced medication errors, greater appreciation for drug interaction potential, earlier identification of toxicity, and earlier guidance on rescue therapy.

Thus, to facilitate the identification of toxicity-related genes, we compared gene changes in a nontarget tissue for toxicity the kidney with those of the target organ of methapyrilene toxicity the liver in addition to analyzing gene expression changes across dose level and number of doses.

These approaches, when applied to toxicology, are termed 'toxicogenomics' and promise to greatly facilitate mechanism-based research on toxicant action with the longer term possibility of assisting in the identification of potential toxicity issues earlier in the development of new pharmaceutical, agrochemical and chemical products.

This work was followed by intensive research to establish an in vitro system combining liver cells and metabolomics for the identification of liver toxicity and modes of action.

It has been observed that identification of liver toxicity can indeed be achieved by in vitro metabolomics using the HepG2 liver cell line.

The identification of renal toxicity was performed using serum creatinine, urinalysis, and other signs and symptoms of kidney injury.

Thus, insulin-secreting cells are an appropriate model system for identification of mitochondrial toxicity and its functional consequences following antiviral therapy.

Since NAO-related features will be correlated to mitochondrial function and structure, this assay should be useful for early identification of drug toxicity.

To this end, the robust demonstration of altered rates of development due to test compound exposure will also provide additional information for interpretation of the effects of the test compound on gonadal development (e.g., identification of systemic toxicity).