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Zeng, C. et al. Identification of susceptibility loci and genes for colorectal cancer risk.
One popular view proposes that mapping efforts should focus on identification of susceptibility mutations that are relatively old and at high frequency.
In particular, the identification of susceptibility genes, elucidation of the role of inflammation and an increased understanding of the molecular changes that occur during multistage pathogenesis should be important goals for the future.
The linkage approach to quantitative traits, such as estimated glomerular filtration rate (eGFR), has been utilized in several recent studies aimed at identification of susceptibility loci.
Working memory (WM) impairment is a promising candidate endophenotype for schizophrenia that could facilitate the identification of susceptibility genes for this disorder.
The power of GWA analyses has been recently demonstrated with the identification of susceptibility genes involved in dementia-associated imaging phenotypes like intracranial volumes, or size of the hippocampus.
Similar(13)
His work has led to the identification of significant susceptibility quantitative trait loci and functional characterization of candidate genes for susceptibility to lung injury induced by environmental pollutants.
These observations imply that identification of new susceptibility factors in a complex disease may depend on classification of families by mutational type at known susceptibility genes.
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.
Thuong, N. T. et al. Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.
This study deals with reliable identification of frost susceptibility of recycled concrete aggregates.
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