Sentence examples for identification of new compounds from inspiring English sources

Therefore, identification of new compounds able to discriminate UII- and URP-associated biological activities is crucially needed.

In this context, the molecular modifications or synthesis of compounds continue being the best strategies for the identification of new compounds for the treatment of pain and inflammation.

It resulted that only GTP decreases the formation of the GBP1 PIM1 complex through an allosteric mechanism, putting the bases for the identification of new compounds potentially able to revert resistance to paclitaxel.

Such alignments can be used for similarity-based identification of new compounds by using known active template structures as seeds.

The tools of biotechnology are becoming increasingly important in all phases of drug discovery, including identification of potential molecular targets, the production and identification of new compounds as leads, and the development of new leads into useful drugs.

This will make identification of new compounds which are effective in only a small subset of patients easier.

9 Due to the limitations of the current treatments for HAT, there is a need for the identification of new compound classes displaying antitrypanosomal activity.

The timely convergence of all these affordable methodologies, amenable to fairly small sample size such as tissue biopsies, MACS sorted cells (magnetic activated cell sorting), and cultured cells, combined with advances in genome editing technology, will accelerate the identification of novel targets and the development of new compounds.

Moreover, new reactions were added to the model based on the careful revision of the genome annotation that allows the identification of gene functions previously not included, as well as the incorporation of new compounds into the biomass equation.

The identification of this class of proteins in A. euteiches will allow the development of new compounds acting on Saprolegniale pathogens.

A subsequent screen of the library led to the identification of several new compounds with potent anti-fungal activity in vitro against both yeast and hyphal forms, low cytotoxicity to human cells, and strong in vivo activity in two different mouse models of oral candidiasis25.