Sentence examples for identification of master from inspiring English sources

His lab, which integrates both experimental and computational research, has pioneered the first genome-wide regulatory model of human cells and a variety of methods for the identification of master regulators of aberrant transformation and physiological differentiation/maturation events and their controlling genetic alterations.

The identification of master transcription factors, which execute reprogramming, represents significant progress in the understanding of mechanisms of induced pluripotency.

However, the identification of master genes and key biological processes involved in the initiation of liver compensatory growth after removing the ventral lobe remains a challenging task.

To mention only a few examples, application of signal processing has led to development of more accurate tools for prediction of transcription factor binding to gene promoters, which is a necessity for identification of master regulators [11].

The network approach enabled the identification of putative "master" sequences and provided evidence that within a genus these master sequences are associated with distinct U3 regions.

The identification of a master regulator that regulates the entire ligninolytic system in white-rot fungi could be used as a target for breeding a high lignin-degrading strain and for furthering our understanding of the lignin-degradation system in these fungi.

This leads to two possible explanations; 1) Different DR protocols impact upon different pathways, each of which are dependent upon specific regulators or 2) sub-optimal DR regimes can result in false-positive identification of potential master regulators.

This has allowed the in-depth dissection of pluripotency circuitry and identification of the master pluripotency genes Oct4, Nanog and Sox2, which have been employed to generate iPSCs.

This strategy has already been proven successful for the identification of the master SD gene in the rainbow trout (Yano et al. 2012).

We focused our analysis of differentially transcribed genes on the identification of putative master regulators that might drive expression of the embryo transcriptome, with an emphasis on epigenetic regulators and transcription factors that could potentially impact development.

The absence of bias is further revealed by the identification of possible master susceptibility loci for different cancer types, such as the convergence of risk variants at chromosome 8q24 [ 3, 5- 12].