Observation of both the GO analysis and manual assignment identification of functions was used to assign genes to functional groups.
In contrast to proteins, lncRNAs with similar functions often lack linear sequence homology; thus, the identification of function in one lncRNA rarely informs the identification of function in others.
Figure 1 Appearance of the TB Mobile app and identification of functions on an iPhone.
There is reason to believe that a rapid determination of a protein fold, even at low resolution, can aid in the identification of function and expedite the determination of structure at higher resolution.
Structure-based phylogeny of cupins can influence identification of functions of proteins of yet unknown function with cupin fold.
Experimental identification of function of one such domain might help in inferring the functions of clustered domains.
The Gene Ontology analysis allows the identification of functions affected in the system under study, rather than individual genes.
However, identification of function-related and structure-related amino acid positions is only possible after a detailed study of every protein.
Thereby, doors to faster identification of function and a greater understanding of biological pathways are opened.
We would like to thank Hani Goodarzi (Princeton University) for his help in identification of function-specific motifs.
