The level of collision energy is very important to the sensitive identification of focused molecules; therefore, optimal conditions for detecting the appropriate precursor ion and neutral loss were determined by preliminarily analyzing PC (diacyl-16:0/18:1) as standard lipid.
The radiolabeled leucocytes can be considered as gold standard for the identification of inflammatory foci in the intestine and bone tissues (Weiner [1990]).
These indications include: investigation of dental disease, identification of inflammatory foci, vascular lesions, muscle and tendon pathology, assessment of physiological function of the lungs, gastrointestinal tract and other organs.
In addition to the study of these disorders, the most widespread utilization of MEG is in the identification of epileptic foci in pediatric epilepsy [21].
BLI allows spatiotemporal identification of infectious foci in living hosts (Contag et al., 1995; Doyle et al., 2004).
Epidemiologic observations concentrate on descriptive information or identification of new foci; however, few case-control studies have been published (2, 3, 9 ).
There may also be a role for this technique in the investigation of postprostatectomy patients with a rising PSA; identification of abnormal foci of enhancement in the prostate bed may indicate local recurrence and guide needle biopsy for histological confirmation.
We have developed a medium throughput phenotypic assay, based on the identification of nuclear foci in DM patient cell lines using in situ hybridization and high-content imaging to screen for potentially useful therapeutic compounds.
Identification of such foci would provide the opportunity to investigate transmission among wild animals and pigs in agro-ecosystems and the variables that influence transmission, such as climate, pig farm size, herd size, and pig exposure.
