Sentence examples for identification of driver from inspiring English sources
This variation can confound the identification of driver mutations outside non-coding regions.
The identification of driver loci underlying arm-level somatic copy number alterations (SCNAs) in cancer has remained challenging and incomplete.
However, the genetic complexity of human cancer has complicated the identification of driver mutations among the more abundant passenger mutations found in tumors.
More recently, new sequencing technologies have allowed the identification of driver mutations in epigenetic regulators, providing a mechanistic link between the cancer epigenome and genetic alterations.
Although the field of epigenomics in cancer is relatively new, the identification of driver mutations in epigenetic regulator genes has already led to new prognostic and therapeutic advances.
When incorporated with disease related information by biochemical and genetic manipulations, human disease models can be established and used for identification of driver mutations and key pathophysiology pathways in disease conditions.
The application illustrates how the proposed framework allowed the identification of drivers for potentially disruptive change and their implications on Italian MNOs' business models.
the gathering of relevant information around the theme, the search for contacts and possible participants for workshops or interviews, the identification of drivers with potential impact on the development of NCDs in the future.
If standard definitions of the Foresight method imply outlining a focus and a horizon, and conducting a Foresight diagnosis through the identification of drivers and the building of scenarios, there are certain key circumstances that call for different methodological needs which are not totally identified.
The foresight approach used in the project consisted in the identification of drivers and barriers for long-term (15 20 years ahead) change, which was followed by the construction of micro-scenarios, by 20 panels of experts and stakeholders, covering the major sectors of the Greek economy and society.
