These regions are particularly desired for some short DNA sequencing applications, such as the identification of DNA damage hotspots and DNA replication stalling sites (Zhou et al., 2013).
Identification of DNA sequences specific for V. vulnificus biotype 2 strains by suppression subtractive hybridization.
Rieder, M. J., Taylor, S. L., Tobe, V. O. & Nickerson, D. A. Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome.
Reider, M. J., Taylor, S. L., Tobe, V. O. & Nickerson, D. A. Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome.
Lewis DA, Jones A, Parkhill J, Speert DP, Govan JR, Lipuma JJ, Lory S, Webb AK, Mahenthiralingam E. Identification of DNA markers for a transmissible Pseudomonas aeruginosa cystic fibrosis strain.
In this study, a surface plasmon resonance DNA biosensor based on RCA with a gold (Au) nanoparticle surface was established for isothermal identification of DNA.
PCR-RFLP (Polymerase Chain Reaction-Restriction Fragment Length Polymorphism) identification of DNA regions is an available technique; however, primers which have a high probability of amplifying only the basidiomycete DNA are needed.
The compelling evidence that stabilizing these motifs by small molecule ligands can alter cell viability in certain cancer cell lines has led to identification of DNA quadruplex structures as therapeutic targets.
Since morphological cell transformation is strongly associated with mutation and/or larger scale DNA damage in C3H10T1/2 cells, the identification of DNA damage induced in these cells by trans-B[a]P-4,5-diol was sought.
* From the identification of DNA arrays within microbes and mitochondria that shared much of the same sequence(Mojica et al. 2000) to figuring out spacers between these shared sequences are mostly from foreign DNA(Bolotin et al. 2005) and can provide immunity to viral infection(Barrangou et al. 2007).
Moreover, GBS approach is a powerful method to develop high-density markers even lack of the sequenced reference genome or previous identification of DNA polymorphism.
