Sentence examples for identification of culprit from inspiring English sources

Myocardial perfusion scintigraphy (MPS) is widely regarded as a clinically useful noninvasive imaging method for the diagnosis of suspected coronary artery disease, identification of culprit lesions and risk assessment [1 4].

In the case of breast cancer, continuous treatment of HER2-amplified PDX models with trastuzumab could provide a useful preclinical tool to eventually overcome HER2 resistance through the identification of culprit pathways.

While some authors prefer less emphasis on identification of culprits and their punishment, others argue that stiffer punishment and, in fact, criminalization of scientific misconduct is needed to reduce its prevalence [ 27- 29].

Historically, there are two main approaches to the identification of the culprit gene in these cases.

Identification of the culprit genes underlying multifactorial diseases is one of the most important current challenges of molecular genetics.

Clinical signs of infection are nonspecific and the identification of the culprit pathogen is not available in the early hours.

This comprehensive information improves both the identification of the culprit vessel and the diagnostic confidence for categorizing intermediate lesions and equivocal perfusion defects, thus optimizing management decisions.

Traditional antibiograms display the percentage susceptibility of each common bacterial pathogen to each common antimicrobial agent, but this does not help clinicians select an empiric antimicrobial regimen prior to identification of the culprit pathogen.

Identification of the culprit genes underlying these inherited CVDs has allowed genetic testing in families with affected members, therefore allowing counseling and prevention in asymptomatic carriers (Tester and Ackerman, 2011).

One useful strategy to identify such genes is forward mutagenesis, in which the mouse genome is randomly mutated to yield phenotypes of interest, followed by identification of the culprit mutations.

See related Research: http://genomemedicine.com/content/4/12/103 For many Mendelian phenotypes, identification of the culprit gene and its alleles is often insufficient to understand the disease, as the penetrance of these alleles is largely dependent on the genetic background.