Sentence examples for identification of altered from inspiring English sources

Trushina, E., Dutta, T., Persson, X. M., Mielke, M. M. & Petersen, R. C. Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics.

The identification of altered gene expression profiles with microarrays is best viewed as the first step in the determination of potential disease-associated genes; however, the false-positive rate can be high, particularly with small sample sets and in view of the typically small differences observed in brain expression studies.

An alternative approach for molecular dissection of SCZ is identification of altered gene expression in affected tissues.

For the identification of altered (gained or lost) DNA regions, a threshold was established based on the changes observed in the log2 CN values (fluorescence intensity ratio) of sequential tumour DNA segments found for each individual.

MMPs and TIMPs have been also investigated as potential markers for dementia, resulting with the identification of altered plasma levels of MMP-9 and TIMP-1 in Alzheimer's Disease and vascular dementia, respectively [27].

Consequently, functional pathway mapping technology that can directly measure the activation state of hundreds of proteins in signalling transduction pathways (STPs), can hold great promise for the identification of altered STPs in tumour cells.

The discovery power of the optimized column configuration was illustrated by identification of significantly altered phosphopeptides harboring novel sites from proteins previously established as important in T cell signaling including A-Raf, B-Raf, c-Myc, CARMA1, Fyn, ITK, LAT, NFAT1/2/3, PKCα, PLCγ1/2, RAF1, and SOS1.

If anti-cancer drugs are labelled for specific mutations, robust and reliable diagnostic tests are needed for the identification of the altered genotypes in tumor material.

Identification of significantly altered genes revealed only little changes for the exposure of HaCaT cells to WC.

The identification of these altered molecules and their correlations with clinical and pathological stages may help to elucidate the mechanisms involved in this processes.

Because the identification of genes altered in multiple condiions was a major objective of this study, a nested F-test approach was employed as this can be more powerful at detecting genes altered in multiple contrasts.