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Thus, markers enabling identification of aggressive component are of great interest.
Allred scores of 7-8 were considered suitable for the identification of aggressive advanced gastric carcinoma.
These findings may assist improved biomarker identification of aggressive forms of colorectal adenocarcinoma.
This study provides new evidence in support of the potential of Ep-ICD and EpEx when incorporated with ESLI to serve as markers for identification of aggressive PTMC from non-aggressive PTMC.
Interestingly, miR-181a, one of the miRNAs down-regulated after formaldehyde exposure, was reported to affect the DNA damage response in breast cancer, enabling the identification of aggressive breast tumors based on increased miR-181a expression (Bisso et al. 2013).
However, physicians need an accurate grading determination in two different settings: (1) In patients whose first-line treatment is surgery, the identification of aggressive pathological features from the core biopsy can select patients who will require adjuvant chemotherapy.
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In addition, it indicates that baseline CTC determination enables identification of more aggressive disease and thus may be valuable in making an early decision whether patients require more aggressive or less aggressive treatment [ 15].
Identification of specifically aggressive clusters of cells would allow their selective removal.
In the case of M. tuberculosis, one of the outcomes of genetic typing has been the identification of particularly aggressive or successful strains.
Taken together, a dramatic breakthrough has come with the identification of the aggressive and invasive effects of TNFAIP8 in tumours.
Therefore CB techniques may allow identification of more aggressive cancers, which is important for defining prognosis and deciding adequate treatment.
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