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In addition to genome-wide eQTL identification, combinations of eQTLs and lead SNPs identified by GWAS have been provided to interrogate the mechanisms underlying disease susceptibility at specific loci (Grundberg et al., 2009; Nica et al., 2010; Zeller et al., 2010).
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To the best of our knowledge, there is no standalone tool which allows the visualization and comparison of pseudo peptides found in different experimental conditions and which imports identifications from mzTab [ 9] format and thus supports any peptide identification, combination of identification algorithms or post-processing algorithm.
In difference from previous works, our framework allows the identification of combinations of any size; moreover, these combinations are allowed to occur non-contiguously along the protein.
Biotechnologists that tinker with the metabolism of microorganisms to produce valued products look at the engineering process through the lens of the so-called 'design-build-test cycle.' The idea is that multiple iterations of this cycle ultimately allow the identification of combinations of genetic and metabolic elements that produce the highest levels of a desired drug or chemical.
The results show that concept analysis and mapping can be used to analyse FiT designs enabling identification of combinations of discrete elements including fixed and variable payment rates, differing levels of market regulation and competition, varying tariff operating periods, and eligibility rules for RE system sizes, development sites and low emissions technologies.
However, the probabilistic and PCA approach enabled a more holistic evaluation of sensitivity, including identification of combinations of alignment parameters that most significantly contributed to kinematic and contact mechanics outcomes throughout the flexion cycle, and the predictive capability to estimate joint mechanics based on alignment conditions without requiring additional analysis.
MDR allows reducing the dimensionality of SNP data improving the identification of combinations of polymorphisms associated with disease risk.
One prerequisite for the development of personalized medicine is the identification of combinations of biomarkers to guide a physician's clinical decision.
Identification of combinations of transcriptional regulatory elements from large amounts of DNA sequences can benefit greatly from proposed bioinformatics methods as the multiple alignments and the LGM.
Logic regression is a machine-learning procedure which allows for the identification of combinations of variables to predict an outcome, such as the presence of a vaginal infection.
PicTar also depends on the seed region complementarity and its most distinguishing feature is its probabilistic identification of combinations of target sites [82].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com