For case identification, a cut-off point of ≥11 will be applied [ 44].
To control for this formal possibility in the human-mouse ortholog identification, a cut-off based on the distribution of dS for human-mouse was employed.
ROC curves were built, aimed at the identification of a cut-off average score in the first semesters that would be able to predict low performances in future semesters.
The identification of a cut-off with adequate utility for clinical decision-making requires large studies and independent validation.
It requires large studies and independent validation to evaluate inter- and intraobserver variability and the identification of a cut-off value with adequate utility for clinical decision making.
Nevertheless, the difficulty in identification of a cut-off explains the very high number of false positive lesions on WB-DW-MRI, which in general detected two-thirds of lymphoma lesions.
The BLAST program was used for initial identification using a cut off of E-value of 10−3 [10−3
For identification of syntenic regions, a cut-off BLASTn score (<10−10) was applied between chickpea genome and the above six legume plant genomes.
The MASCOT MudPIT peptide identification score was set at a cut-off of 20.
Cheminformatics-guided selection of few representative molecules of a rationally designed virtual combinatorial library is a powerful tool to confront this challenge, speed up hit identification and cut off costs.
Alcohol use was measured using the 10-item WHO Alcohol Use Disorders Identification Test (AUDIT) [ 14], using a cut-off of 16 to define alcohol misuse [ 15].
