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Another application of the scoring function is the identification of interaction partners for orphan SK and RR proteins, i.e., SK or RR genes, which are located in isolation in the genome and consequently do not have easily identifiable interaction partners.
The most direct identifiable interaction would be through the canonical Wnt signalling pathway up-regulating phosphorylated-Smad, the major effector of canonical BMP signalling.
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Based on snapshots from the MD simulations, the replacement of asparagine by tryptophan does not generate easily identifiable interactions such as hydrogen bonds or stacking between the tryptophan aromatic ring of its –N(H)– group and the rest of the receptor molecule or nearby atoms of IFN- γ-SC.
Because of the large number of alternative routes, we conclude the signalling pathways as they are commonly understood in the literature are topologically non-identifiable in interaction databases given current experimental technologies and practices.
These new equations specify media capacity, characteristic size and analyte concentration that are necessary to obtain identifiable responses from interaction with anisotropic porous media or chromatographic resin.
In others, it is explained by the presence of iterated interaction between re-identifiable individuals (Trivers 1971; Axelrod and Hamilton 1981).
Almost every residue in this conserved linker plays an identifiable role in stabilizing the protein DNA interaction.
Local adaptation is identifiable when there is a significant interaction between genotypes and environmental conditions, such that the local type outperforms other types in its own environment (Kawecki and Ebert 2004).
It was determined that this study did not meet regulatory criteria for research involving human subjects because the research did not obtain data through intervention or interaction with the individual or identifiable private information.
Human subject means a living individual about whom an investigator (whether professional or student) conducting research obtains (1) Data through intervention or interaction with the individual, or (2) Identifiable, private information.
The IRB determined that the research does not meet the regulatory criteria for research involving human subjects because there were no interaction with the donors and no identifiable private information.
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