This report constitutes a prospectively planned meta-analysis combining two almost identical trials undertaken in Australasia and Canada to study the effect of starting chemotherapy immediately in asymptomatic patients with metastatic colorectal cancer.
When data are combined for identical trials undertaken in all four participating countries, power will be sufficient to demonstrate a significant reduction in incidence of LBW between Arms 1 and 3 with a trend for decreasing perinatal mortality.
The design was validated by undertaking identical analyses comparing the effects of maternal smoking in pregnancy on birth weight, where effects are known to be causal (11 16).
Although vitamins D2 and D3 have previously been described as undertaking identical hydroxylation processes, which, thus, result in the same active metabolite (calcitriol), data have arisen to show that, in comparison, there may be a difference in their respective efficacies in the raising of serum 25(OH D (4– 7), which is the established marker of vitamin D status (1).
This is a reasonable contribution to the literature in that it would prevent other researchers from wasting time undertaking the identical experiment.
Most recently, Reid et al, [ 6] showed that graduate-entry and undergraduate-entry medical students undertaking an identical clinical curriculum performed similarly on academic assessments of clinical skills.
Such frameworks have a range of features and requirements related to the architecture, protocols and methods of operation, and it is difficult to compare the modelling workload and performance of alternative frameworks without using them to undertake identical, or similar modelling tasks.
An identical screen was undertaken on the entire human genome from Ensembl (50) [40], resulting in the identification of 274 promoters which were designated the RpZRE3-promoter-274 RpZRE3-promoter-274 RpZRE3-promoter-274
Considering an identical screening programme undertaken on the early cohort (2003), the cost per life year saved was £1651 (Table 4).
Meta-analysis of studies which used identical CDR was undertaken in two cases: the 'Rackoff rule' to examine bacteraemia, 22,26,28,34,36 and the 'Santolaya rule' for serious infectious complications.
First, iterative removal of those items with the lowest item-total correlation was undertaken, identical to the procedure previously used to derive the ICBM10.
