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The assumption that the dissociation constant (Kd) and inhibition constant (Ki) for allosteric inhibitors are identical might be an oversimplification.
Possibly, the reason why only 6 of 21 networks were identical might be because of differences in the sets of focus molecules which are generated from p-values and fold change values of differential gene expression that are used in IPA algorithms.
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Therefore, activation observed only in the non-identical conditions may have most likely reflected stimulus-related effects, while activations seen in both identical and non-identical pairs might be related to the task manipulation (i.e. particular attention paid to stress or vowel differences).
Even for the same date, an identical room might be available at $250 through an online reservations service that stockpiled a block of such rooms at a discount from the hotel.
Identical arrays might be built for the analysis of the TCRα, -γ and -δ repertoires and of the B-cell receptor repertoire in humans and other species.
But would this not also be the case with unstable isolations if the tuning of adjacent neurons is nearly identical, as might be expected given the columnar nature of responses in the visual cortex [35], including the inferotemporal cortex [7]?
Thus, although mechanisms cannot be identical, there might be some overlap between the tetrapod DM and the teleost non-classical class II functions in aiding classical class II molecules.
If the two trial designs and patient populations are identical, there might be a possibility for developing a mapping algorithm in the first trial and predict utilities for the second.
Biofilm formed by genetically identical eukaryotic cells might be considered as a primitive form of multicellularity.
This does not suggest that the pathogenesis is identical, but there might be some common immunological pathways involved.
The observed variety in prevalence of impacts using identical OHRQoL instruments might be due to differing perceptions of oral health in different populations or to reporting biases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com