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Ideally, targeted therapies would be tailored to the genetic mechanisms responsible for a particular patient's tumor.
Due to systemic side effects of adenosine focal adenosine augmentation – ideally targeted to an epileptic focus – becomes a therapeutic necessity.
Ideally, targeted mtSNPs should retain the maximum level of discrimination power in a single mtDNA test and, therefore, a careful selection of mtSNPs for mini-sequencing assays is a key step in the process.
A key component of early goal-directed therapy is the administration of fluid therapy, ideally targeted to physiologic endpoints.
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Therefore, development of an efficient SF inhibitor should ideally target only the splicing activity of the factor, without interfering with its other activities.
Although the characteristics and S-curve percentages are generalizations, developers should pay attention to this curve and ideally target each group with a different diffusion strategy (Green and Johnson [1996]).
The left hemifield was chosen as the location of the sound stimuli to ideally target the right-hemispheric brain areas, which are more responsive to the spatial quality of sound [1], [2], [44], [68] [71].
Methane mitigation interventions should ideally target features that are conserved across all rumen methanogens, so that all methanogens are affected and no unaffected species can fill the vacated niche.
Many patients require a combination of therapies each ideally targeting different pain mechanisms.
Further research is needed to quantify target concentrations and compare adult and pediatric systemic and ideally target site drug exposures at a wide range of dose levels.
New clinically useful β-lactamase inhibitors need to have a significantly broader inhibitory spectrum, ideally targeting all serine β-lactamases (classes A, C, and D).
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