Influenza vaccine potency assays should ideally be generally applicable so that the same method can be used to quantify antigenic forms of rHA from both influenza A and B viruses.
Ideally, the assays should be applicable to intact mammalian cells, including cultured primary cells.
Ideally, this questionnaire must be applicable to a wide range of patients receiving anticoagulant therapies and must also address issues related to treatment attributes such as the route of administration (e.g. subcutaneous versus oral).
Ideally, this test would be applicable to early disease, but to do so it must overcome the "blood dilution" problem: that is, if 10 initiating cancer cells release 1000 molecules each of a biomarker into two liters of blood at steady state, the concentration of this biomarker would only be 1.3 × 10-14 M [ 12], placing it below the detection limits of even the best assays [ 12].
Ideally, any marker type would be applicable to several species to enable cross-species comparisons and allow investigation of karyotype and genome evolution.
Ideally, a screening method would exclusively identify substrate phosphorylation site inhibitors, would be applicable to any kinase of interest, and would not require structural knowledge of the target or the development of multiple probes for different targets.
To be applicable in the clinical setting such tests will need to be ideally readily deliverable at regular clinic visits.
Ideally, this measure would be sensitive to chronic hyperglycaemia, glucose variability, and hypoglycaemia, and be applicable in routine diabetes care for the screening of profiles with insufficient metabolic control.
"It could be applicable anywhere".
Thus, an exercise can ideally be designed as a collaboration exercise when it is applicable to different situations and provides the individual with relevant challenges.
