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An ideal specificity is to reach the level where the substance can be detected in the presence of many contaminants.
This proposed method for S. mutans detection possessed some attractive characteristics such as facile manipulation, short detection time, low cost, ultra-high sensitivity and ideal specificity.
The protocol showed an ideal specificity for S. mutans detection because the recognition agents bound with the bacteria at two distinct sites.
To achieve ideal specificity for S. mutans detection, rat immunoglobulin G2a (rat IgG2a) tagged with horseradish peroxidase (HRP) was used as the second recognition agent and signal tracer since Fab region of rat IgG2a could bind with streptococcal protein G highly expressed in the cell wall of S. mutans.
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Hemin was proven to not only serve as the catalytic center but also play an essential role in molecular recognition; the multiple-site interactions between the plural co-monomers and the substrate may overcome the interference of water molecules during molecular recognition and confer on the MIP an ideal substrate specificity toward template and catalytic activity even under aqueous conditions.
Although the sensitivity for this test was found to be 100% which is considered ideal, the specificity was found to be 0%.
This level of analysis can be referred to as "meso-history," and it appears to offer an ideal mix of specificity and generality.
With Dacia Literară, Kogălniceanu began expanding his Romantic ideal of "national specificity", which was to be a major influence on Alexandru Odobescu and other literary figures.
Urine sCD163 concentrations also had an ideal sensitivity and specificity for the diagnosis of sepsis.
Complementary DNA methylation biomarkers that reach an ideal sensitivity and specificity rather than a single one for detecting CINs have not been successful so far.
Unfortunately the study design employed by Apfalter et al. was not ideal for assessing specificity as only one negative control was employed.
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