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Several animal models are used to study Mycobacterium tuberculosis (MTB) infections, but none is a fully ideal model of human disease.
In theory, Pacific migration ought to be an ideal model of human migration.
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An ideal model of the human GI tract faithfully replicates the ecology of the gut.
Leprosy, an ideal model of a chronic human complex infectious disease, provides an opportunity to dissect the components of the host-dependent polygenic susceptibility to this disease.
CXMDJ is an ideal model of multi-exon skipping, and we hope to translate the results to human patients.
And what are myths, after all, but the most ideal model of the dominant role models of a culture.
Because the MCD diet is deficient in nutrients, it is not an ideal representative model of human NASH because the intrinsic nutritional factors observed in the human diet are not represented in the MCD diet.
As outlined earlier, it is clear that there is no ideal animal model of human stroke, and that the current design of preclinical experimental stroke studies offers substantial room for improvement.
Ideal animal models of human neuropsychiatric disorders should not only phenocopy relevant human symptoms, but the phenotypes should also be based on similar underlying mechanisms acting both physiologically and genetically (Crawley, 2004).
Some geneticists say that because of their detailed pedigree and the similarity of their genes to those of humans, dogs make an ideal model for studying human behaviors and pathologies, especially those involving complex patterns of inheritance.
Since the development of obesity in NEP-deficient mice starts at 6 7 months, this is an ideal model for typical human late-onset obesity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com