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The ideal design is thus to establish pairs of individuals (one of each species), with each pair grown producing descendants in physical isolation from other pairs, ultimately resulting in isolated colonies of different genotype pairs.
Thus, an ideal design is a multi-method approach that leverages the advantages of both field and laboratory methods.
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Can the ideal design be synthesized?
"It's really sturdy; our ideal design was exactly what we have, which is light on all four sides," Ms. Walker said, "where you see every kind of cityscape".
Though the ideal design was found to be dependent on the specific application, a number of general recommendations are made.
For comparison, the PSFs generated numerically using the measured mask (from profilometer data), as well as the ideal design, are shown in Figs. 4(b) and (c) respectively.
An ideal adaptive design is one where patients are treated as effectively as possible without sacrificing the potential learning or compromising the integrity of the trial.
However, having served on numerous study-design committees of such studies, I have to admit that the ideal study design is extremely difficult to find.
An ideal study design is one that prospectively follows women from close to conception, as this ensures that no pregnancies are missed (and hence the fixed cohort bias is not an issue).
In addition, they noted that the ideal research design is governed by the particular type of scientific question being addressed (Petticrew and Roberts 2003), and many public health questions cannot ethically or logistically be addressed with RCTs.
Methods to select regularities consistently such that they are likely to represent the original, ideal design intent are presented.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com