Meanwhile, the calculation method for joint friction is discussed in detail, and the relationship between ideal constraint force and Lagrange multipliers is derived.
In this paper, a three-dimensional revolute joint model is introduced, the calculation of joint friction is discussed in detail, and the relationship between ideal constraint force and Lagrange multipliers is derived.
These methods, however, do not take into account practical design considerations such as non-ideal constraint behavior.
The design of the squeal model, the steps necessary to perform the stability analysis on systems with non-ideal constraints, as well as the non-smooth dynamics code used to perform the simulations are explained in detail.
A multivariable model including ideal rectal constraints, age, and anticoagulation against patient-reported, global bowel function use indicated that meeting rectal constraints was associated with bowel function (coefficient 4.7, CI 1.0 8.5, P = 0.01), while age (coefficient 0.17, CI −0.04 to 0.4, P = 0.11) and anticoagulation use (coefficient −1.6, CI −6.8 to 3.6, P = 0.55) were not.
The onset of tearing and reconnection, however, may be preceded by the onset of another instability, such as the ballooning instability (e.g., Liu et al. 2012, and refences therein), which operates even under ideal MHD constraints.
Dosimetric data for bladder and rectum were compared to toxicity and QOL global domain scores, specifically analyzing outcomes for men who met ideal rectal constraints (V70 <10%, V65 <20%, V40 <40%).
Bowel QOL remained stable over the 2-year follow-up period and was higher for patients who met ideal rectal constraints (P = 0.05).
Overall bowel function QOL scores at 24 months were higher for the group of patients that met the triad of ideal rectal constraints compared to those who did not (median value 100 vs. 96; P = 0.05).
On UVA, anticoagulation (P = 0.05), older patient age (P = 0.05), and failure to meet the triad of ideal rectal constraints (P = 0.03) were associated with inferior FFG2 GI toxicity.
On univariate analysis, current smoking, larger bladder volume, and higher RT dose were associated with decreased FFG2 GU toxicity, while use of anticoagulation, increasing age, and not meeting ideal rectal constraints were associated with decreased FFG2 GI toxicity (all P ≤ 0.05).
