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It has been selected as an ideal compound lead against TB for further SAR investigation.
KH28 is considered to be an ideal compound for further development as a potential novel antipsychotic.
7,7,8,8-tetracyanoquinodimethane (TCNQ), a strong electron withdrawing olefin, has long been regarded as an ideal compound for the synthesis of semiconducting coordination polymers when coordinated to transition metals.
An ideal compound should have weaker inhibitory effects and higher enhancing activity (Wang et al, 2009).
These qualities make it an ideal compound for development as an anti-fungal agent in the treatment of fungal infections of the oral cavity [ 64].
In comparison, ozagrel was found to be an ideal compound for use as a highly selective TXA2 synthase inhibitor [ 31], and it is in clinical usein Japan.
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Ideal compounds for viral purging would induce viral replication in a wide variety of infected cell types without causing massive T-cell activation and proliferation to prevent the generation of new target cells for the neosynthetized virus, while maintaining the patient on HAART to prevent a spreading infection.
This modulatory property may make tyrosine kinase inhibitors ideal compounds for use in combination with other anticancer drugs.
Compounds were classified according to both the LD50/EC50 ratio (analogous to the therapeutic index) and the maximal enhancement of Treg cell differentiation, with ideal compounds performing maximally for both parameters.
As shown in Table 1, new analogs of 19 were screened against human and rat mGlu1 as well as hmGlu4, generating significant, tractable SAR with ideal compounds showing equipotent activity at both human and rat mGlu1 to support future translational studies.
The faster kinetics for Li transport combined with structural changes which are minimized in the quasi-ideal compound explain the lack of notable polarization voltage and the good cycle life of the latter cathode material with a stable capacity of 140 A h/kg over 40 cycles at C/10 rate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com