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AA contributed with the overall design idea, revised the manuscript and approved the final version.
KN developed the project idea, revised the manuscript, participated in discussions and supervised the overall project.
EMB, MH and BDS contributed with the overall design idea, revised the manuscript and approved the final version.
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All authors contributed ideas, revised different drafts of the manuscript and approved the final version.
All authors gave ideas, revised, read and approved the final manuscript.
Wrote the paper: MVC, AO, MS. All the authors contributed ideas, revised different manuscript versions and approved the final one.
YZ wrote this paper and analyzed the results of the experiments; JW proposed the initial idea and revised this manuscript; QS carried out the simulations and revised this manuscript; WG conceived of the experiments.
LL, XZ, ZL, LW and QZ proposed the idea and revised the manuscript.
ST conceptualised the idea and revised the study protocol, especially the research design and data analysis.
TAA established the idea and revised the work as well as supervision of PICU management of the patients.
YT, JC and WY carried out the calculation and analysis, AK and CL participated in the discussion of the project and drafted the manuscript; BS conceived the idea and revised the manuscript.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com