Sentence examples for i was mediated from inspiring English sources
Davis et al. showed that the adhesion of melanoma cells to native collagen type I was mediated by several β1 integrins, including α2β1, as well as some αVβ3.
To assess whether growth inhibition by irradiation/cisplatin/ICI was mediated by apoptosis, HeLa cells were stained with Annexin V-PE and 7-ADD for flow cytometric analysis.
We found that the delay in the growth of U87-EGFRvIII cells in co-culture with hMSC-scFvEGFRvIII is mediated in part through down-regulation of pAkt in U87 cells.
We show here that the translation mechanism for synthesizing cryptic peptides for presentation by MHC I is mediated through recognition of non-AUG initiation codons by ribosomes during the initiation step.
We were not able to examine the hypothesis that the disease association of the polymorphism at +1127 INS-PstI is mediated through altered insulin levels.
However, we have found that the cytotoxicity of GSI I is mediated by proteasome inhibition rather than γ-secretase inhibition [ 27].
This suggests that the anti-fibrotic effect of albumin and R-III is mediated, at least in part, by downregulation of RA signaling.
Phospholipid binding of synaptotagmin I is mediated by its C2-domains which bind preferentially the negatively charged phospholipids PS and phosphatidylinositol [ 48, 49].
Phase I is mediated largely by cytochrome P450 (CYP) enzymes, which are a family of xenobiotic enzymes that are responsible for de-toxifying cigarette smoke and other environmental irritants into intermediate metabolites.
The hepatic and renal excretion pathways of [99mTc]MIBI are mediated by P-gp, and modulation of P-gp transport function can be detected in humans when this radiopharmaceutical is used with cytotoxic drugs.
The protective effect of IGF-I involved blockade of the activation of FOXO 3, a transcription factor involved in brain responses to oxidative stress, by H 2O 2. Inhibition of FOXO 3 by IGF-I was mediated by Akt; i.e.: an Akt-insensitive mutant of FOXO (M-FOXO3) abrogated IGF-I effects while wild type FOXO3 did not interfere with its protective actions.
