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Complex I turnover becomes restricted by the lack of electron acceptor ubiquinone.
In addition to degrading and recycling cellular organelles such as mitochondria, autophagy may also affect MHC Class I turnover.
This implies a distinction between (i) turnover initiated through incorporation of new histones and (ii) turnover primarily due to eviction of old histones.
In summary, we provide evidence that a collagen type I turnover product, PINP, is a potential marker for monitoring fibrosis during chronic liver disease.
Radioimmunoassay was used for the quantitative determination in serum of the collagen type I turnover marker PICP (C-terminal propeptide of type I procollagen) (Orion Diagnostica).
The potential neurobiological mechanisms underlying these differences were explored by measuring (i) turnover of candidate neurotransmitter systems in the nucleus accumbens, (ii) hippocampal neurogenesis by BrdU labelling or by analysis of candidate genes involved in neuronal growth and (iii) changes in mRNA expression of candidate genes in dissected hippocampal and amygdala tissue.
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Post-translational modification of MHC-I molecules by ubiquitin provides a potent mechanism for regulating MHC-I turnover and several viral as well as cellular ubiquitin E3 ligases (Randow and Lehner, 2009) regulate MHC-I assembly in the endoplasmic reticulum and at the cell surface.
He attempted a shot 19 times, committed one turnover, and I repeat: passed twice.
Kentucky leads Division I in turnovers forced (911) and turnover margin (+9.73 per game).
According to this mechanism, two pump modules are driven by two conformational strokes that are generated by stabilization of the anionic forms of semiquinone and ubiquinol that are formed in the peripheral arm of complex I during turnover.
To specifically address type I collagen turnover, biomarkers for degradation (ICTP) and neosynthesis (CICP) were analyzed in conditioned media.
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