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In Phase I studies as well as the two published, Phase II clinical trials, the combination of ceftazidime and avibactam was generally well tolerated.
44 A recent review of the cardiovascular safety profile of dapoxetine has examined data from the complete dapoxetine development program, including preclinical and Phase I studies, as well as the Phase III RCTs included in this review.
This panel has been applied in a consistent manner to smaller, phase I/II studies as well as larger, randomized phase III studies.
We aimed to elucidate associated genes for optic disc parameters using the GWAS platform in the RS I-III studies as well as the family-based ERF population.
This article reviews its implementation, showing the characteristics, advantages and limitations of this method in Phase I studies as an alternative to the classical 'Fibonacci' escalation schema.
α2-Integrin is therefore currently being evaluated in phase I studies as possible biomarker (4, 6).
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I studied as an actor at the theatre conservatoire in Quebec, but by the time I got to my third year I was more interested in directing.
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