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The utility of the approach is demonstrated by (i) separating known similar binding site pairs from random binding site pairs and (ii) a bioisosteric replacement study for fragments binding to subpockets of different proteins.
Our results reveal that there should be two mainly roles for TPBi blocking layer in enhancing the device performance: (i) separating the hole accumulation interface from the exciton formation zone, which prevents the quenching processes of QD emission caused by these accumulated holes, (ii) suppressing the hole leakage from QDs to ZnO.
Dong [ 10 ] cited a variety of sources for these data, including contacting the study authors and searching website and clinical trial registers; these were not included in the present base case analysis (I) Separating patients treated with tiotropium by type of inhaler used (SoftMist or HandiHaler).
Heterozygosity was evaluated by examining the sequence data and by forming a heteroduplex on a single individual sample, applying the mismatch endonuclease Cel I, separating products on a denaturing acrylamide gel, and verifying the presence or absence of the predetermined cleaved fragment.
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