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History -- it helps me keep the past alive, even though by doing so I impair the present.
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NI non-impaired, I impaired.
Growth curves made for each cell line revealed that the introduced mutation HA2 58K→I impaired the yield of the mutant virus VN1203wtNS-K58inin HBE cells of about 150 times.
NI non impaired, I impaired, Ref reference population.
This result suggests that Q555X-hSynI impairs SV mobilization during sustained HFS in inhibitory synapses as a consequence of the reduced RP of SVs.
With regard to benign meningioma (WHO grade I) impaired survival has been previously implicated by data of the Swedish Cancer Registry, based on a patient cohort diagnosed from 1960 to 1998 (Talback et al, 2004).
Exclusion criteria included: (i) impaired speech production, speech comprehension or writing (to rule out those with 'central' alexia); (ii) a premorbid history of neurological or psychiatric illness; or (iii) evidence of visual neglect or visuospatial processing deficits.
Furthermore, once the neurofibrillary pathology reaches the basal forebrain (occasionally already in Braak stage I), impaired retrograde transport of NGF could be the consequence, leading to an accumulation of NGF where it is synthesized (hippocampus and neocortex) and to a loss of NGF in the basal forebrain (Fig. 2).
ACE-i impair the development of kidneys, lungs, and skull ossification they cause intrauterine growth retardation; and even intrauterine demise [ 2].
Interestingly siRNA-mediated knockdown of MDA5 and IPS-1 but not RIG-I impaired interferon responses to MVA infection [37].
In prostate cancer cells, survivin expression has been shown to be regulated by IGF-1 stimulated Akt-mTOR signaling [ 33], which Is impaired upon simvastatin treatment [ 5].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com