"They have recapitulated the elements of healthy, working-class neighborhoods — it's back to the future," said Howard Husock, a vice president for social research at the conservative Manhattan Institute.
Alternatively, biomimetic human "Organs-on-Chips" microphysiological systems have recapitulated the mechanically dynamic 3D tissue interface of human organ microenvironment, in which the transport, cytotoxicity, biocompatibility, and therapeutic efficacy of NPs and their conjugates may be more accurately validated.
Biomaterial approaches have recapitulated the native properties of the TMJ disc, but their in vivo efficacy has yet to be determined.
Xenograft and genetically engineered mouse (GEM) models have recapitulated critical elements of human pancreatic cancer, providing useful tools to probe the underlying cause of cancer etiology.
Although fly models of PINK1 loss-of-function have recapitulated mitochondrial dysfunction and age-related neuronal death, the actual mechanisms remain unclear.
We have recapitulated n-MTB elongation in an interphase nucleus by increasing its length (L) while keeping the other parameters fixed (Fig. S1 and extended discussion in Supplemental Text S1).
Here, we have recapitulated the endogenous physiological anti-LCMV response by transfer of low numbers of virus-specific CD8 T cells with minimal impact on the endogenous anti-viral CD8 T cell response.
Homozygous and double heterozygous transgenic mouse models of HCM have recapitulated increased disease severity and loss of cardiac function similar to phenotypes observed in humans [12], [18], [23], [24], [26] [28].
Indeed, we have recapitulated these effects with the stepwise transformation system (Fig. S7).
Many similar experiments since (e.g. 29– 32), discussed in more detail below, have recapitulated this basic phenomenon.
