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In addition, impaired DNA topoisomerase I functions and perturbation in telomere architecture were observed in cells exposed to micromolar concentrations of IIQ derivatives.
Building on these findings, we will investigate the lysosome as a metabolic 'command and control' center that i) functions as a signaling hub for nutrient sensing and signaling and ii) controls the storage and delivery of key substrates to the cell's metabolic pathways.
The functions are the extensions of V-type I functions presented in [12] and type I functions presented in [14].
It combines three components: the concepts of V-type I functions [12], ( F, α, ρ, d ) -convex functions [13], and type I functions [14].
Weak, strongand converse duality theorems are discussed involving generalized higher-ordertype I functions.
Parametric duality results have been proven under generalized type I functions assumptions.
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