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The introduction of a phenylalanine is predicted to disturb the allosteric site I function as well as the hexameric assembly.. Summarizing, the here-reported missense variants are expected to exert a mild destabilization of the hexameric enzyme structure, although p. (M115V) and p. (V309F) are predicted to have a more severe effect than p. (A113S).
"I live in a sighted world, but I function as a blind person.
Loaded with large memory caches and floppy disk drives (U.S.B. ports are soon to come), machines like Husqvarna Viking's Designer I function as ancillary computers for hobbyists, many of whom augment their sewing workstations with laptops so they can continually update software and stitch patterns.
I function as anyone else would.
But my mother, the art world, and I function as an ever-evolving trio, and while my mother and I each require the other two to sustain, I cannot say that the art world has needed me for anything.
Within a year, without surgery or any hormone injections, just by ceasing to comply with "reparative" female hormone therapy, I function as an intersex masculine person and am not only no longer lingering near death but so robust in health that I make my living teaching yoga.
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They were not my own, but I functioned as a surrogate dad.
Cos Cob, part of Greenwich, was abuzz with artists from the 1880's until World War I, functioning as an Argenteuil for American Impressionists who stayed home.
Like I say, I functioned as a Mad Men expert without seeing Peggy give birth or Betty shoot at pigeons, and it never spoiled my enjoyment of the show.
These data suggest that EWS/FLI functions as a transcriptional activator to mediate oncogenesis in Ewing's sarcoma.
Similarly, evidence has also suggested that EWS/FLI functions as a transcriptional activator, and that this is required for its role in oncogenesis [12], [13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com