Your English writing platform
Discover LudwigSuggestions(2)
Exact(3)
a, The GBM tumour cell line from patient 7 that was established from the initial resection is positive for GBM tumour markers by immunohistochemistry. b, The GBM tumour cell line generated from initial resection tissue of patient 7 has low HLA-class I expression that is upregulated by IFNγ treatment and is negative for HLA-class II DR expression.
As rectal tumors are mainly MSS, our results suggest that it is both, oncogenic pathway and HLA class I expression, that dictates patient's prognosis in colorectal cancer.
Here we have demonstrated that maGSC, ESC, and iPSC lines can be killed by activated peptide-specific CTLs despite levels of MHC class I expression that were below the detection level of flow cytometry.
Similar(57)
By pushing cancer cells to use oxidative phosphorylation instead of glycolysis, metformin can rescue cell surface major histocompatibility complex class I (MHC-I) expression that is downregulated by oncogenic transformation, a crucial adaptation of tumor cells to avoid the adaptive immune response by cytotoxic T-lymphocytes (CTLs).
I like expression that's framed in restraint, that gives a certain dignity to it.
Presumably the low-levels of GFAP and βIII tubulin expression that were detected in eNPC by immunocytochemistry were below the detection threshold for Western blotting.
Together these data show that BNP antibody-mediated complement dependent lysis strongly correlates with MHC I expression and that cells with high MHC I expression are killed predominantly.
The fact that ATF2 phosphorylation was not affected either by inhibiting TβRI kinase activity or knocking down TβRI expression indicated that TβRI was dispensable for ATF2 activation.
Subsequently, we have investigated the frequency of a concomitant loss of HLA class I expression with that of either the β2m molecule or of any APM component.
"I have this expression that I use for people on whom you rely to be accurate: 'If he tells you a flea can pull a plow, hitch him up.' That was Fritz, Mr. Dinkinssaidid.
Her face often registers a "What in God's name is next?" expression that I associate with city parents.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com