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Genes differentially expressed (Log2 fold change) showing a class I expression pattern (P < 0.05).
D and E: macrophage collagen I expression.
Lactate elevated MHC class I expression in monocytes.
Topoisomerase I expression was downregulated following 12 hours of exposure to treatment, and topoisomerase I expression recovered 8 hours after SN-38 was removed.
PRMT1 over-expression rescued lactate mediated increase in MHC I expression.
NK cells selectively attack target cells with diminished major histocompatibility complex (MHC) class I expression.
The SSS I expression increased to peak at 10 DAA, but then declined.
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This was paralleled by hepatic IGF-I expression (p < 0.01).
TRAMP-C2 cells secrete TGF-β and show low MHC-I expression.
The pituitary reduced IGF-I expression post-pubertally whereas the uterus increased expression.
However, the effect of β3-AR on apoA-I expression in vitro is unknown.
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