The time period when the subclone with i drivers prevails in a cell population is defined by the following expression: Δ t i = t i + 1 − t i = 1 s [ ln (1 + 2 s N (i + 1 ) u (N − i ) ) − ln (1 + 2 s N i u (N − i + 1 ) ) ] ≈ 1 s ln (N − i + 1 ) (i + 1 ) (N − i ) i, where i ≠ 0. For i = 0, we have: Δ t 0 = 1 s ln (1 + 2 s u ) ≈ 1 s ln 2 s u.
Therefore, the relative fitness of a cell with i driver gene mutations, j housekeeper gene mutations, k passenger mutations and l mutator gene mutations is defined as: (2) where is the proportion of tumour cells that have p, q, r and u driver, housekeeper, passenger and mutator mutations, respectively.
I've met cab drivers with the same story, old men and young men who moved with their fathers or sons to Damascus when the Golan fell.
By measuring EC - a tracer of traffic particles - as well as by evaluating a group, i.e. truck drivers with direct exposure to traffic, we had the opportunity to distinguish the effects of traffic pollution from those of the general levels of ambient PM in Beijing.
Just when I was considering getting back on the bike I saw a driver with a provisional license cut off a rider in slow-moving traffic.
I have worked with many drivers with Asperger's and A.D.H.D. and have found that there are often undiagnosed visual difficulties.
I rewarded the driver with a great tip, but then, fidgeting with the clunky sliding cab door, I was reminded that nothing escapes Bloomberg's influence.
When I finally got off the bus and entered the bathroom at the Greyhound station, I found a driver with his pants completely down at a urinal.
"I saw 'Taxi Driver' with my father, and he was blown away.
Outside, among the palms, I met a driver with a black Mercedes; French taxis were striking, he said.
