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Therefore, the relative fitness of a cell with i driver gene mutations, j housekeeper gene mutations, k passenger mutations and l mutator gene mutations is defined as: (2) where is the proportion of tumour cells that have p, q, r and u driver, housekeeper, passenger and mutator mutations, respectively.
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"We found really clear evidence that the highest-BMI drivers are at higher risk of having an accident".
Together, these observations imply that (i) driver-network genes have functional importance specific to the TNBC subtype and (ii) integrated analysis was able to reveal candidates that were functionally more important than what could be obtained using the strongest candidates from differential expression analysis alone.
These results suggest that Klf7 acts as an activator of group I drivers and as a repressor of group II drivers.
DRIVER: I am a driver.
Am I good driver?
"The 18th, I hit driver, 6-iron.
"I took driver over the bunker on the right".
Is the driver friend or foe?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com