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b β2 glycoprotein I domain of phosphatidylserine.
We further characterized zebrafish α2 integrin and discovered that this integrin is highly conserved, especially the I domain.
So in this study, fusion genes of h-UTI and domain I, domain I and domain II, domain I, domain II and domain III of human serum albumin were inserted into expression vector pPICZαA, respectively (As shown in Figure 1).
Different fusion genes of h-UTI and domain I, domain I and domain II, domain I, domain II and domain III of human serum albumin (HSA) were inserted into expression vector pPICZαA.
So in this study, fusion genes of h-UTI and domain I, domain I and domain II, domain I, domain II and domain III of human serum albumin were inserted into expression vector pPICZαA, respectively.
Recombinant human and rat-α1 I domain binding to collagens and peptides correlated with the cell adhesion results, showing receptor class- and species-specificities.
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Structural determination of the integrin ligand complexes for both I domain-containing and non-I domain-containing integrins revealed two fundamentally different types of integrin-binding surfaces.
By contrast, the ANTXR1 I domain-PA interaction exhibits a much lower binding affinity (KD = 130 nM) [20].
However, the assembled structure in D-I domain does not possess the hexagonal characteristics as that of D-II.
The α2-I domain gene incorporating KpnI and SacI sites was synthesized by Shanghai Difa-Bio Ltd. (Shanghai, China).
All these genes encode proteins with an IGFBP domain and a thyroglobulin type-I domain.
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