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I'll get on with affecting what I can affect".
If I think something can change and I can affect change, then I'll do it".
If I can affect that condition, I'm a very happy guy".
"I cannot save the world or make everything better," Dimakou admits, "but I can affect the things around me.
I have in the past tended to overestimate the amount of change I can affect in the short run and then not fully appreciate the change I can affect in the long run.
"Deep inside I feel I have got two real gritty years left in me, the years in which I can affect things.
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In addition to these cellular effects, binding of insulin and IGF-I can affect the release of downstream factors, promoting secondary effects through the body.
I know the actions I take can affect my staff long-term.
Thus, chromatin-associated class I KDACs can affect gene transcription on several levels (Fig. 2).
These group I mGluRs can affect Ca2+ signaling via activation of phospholipase C and IP3 generation (Skeberdis et al., 2001; Topolnik et al., 2006).
Mutations that alter the sequences of the triple helical domains of the chains of type I procollagen can affect the thermal stability of the molecules (12, 21), interfere with secretion efficiency (22), disrupt the chain register (23) or interfere with ligand binding or other interaction sites (5, 24).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com