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DC infected by pathogens upregulate HLA class I, become resistant to NK-mediated lysis, and express CCR7, thus acquiring the ability to migrate to secondary lymphoid organs where the adaptive immune response takes place [3].
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However for those women whose symptoms respond to antibiotics there is considerable anxiety about the prospect of resistance developing; ' I also worry that I will become resistant to this too and then I will be left without an antibiotic which works for me' (Petra).
As shown in Figure 2A, type I survivors became resistant to bleomycin after complemented with a plasmid-borne TLC1, suggesting that the sensitive phenotype of type I survivors was attributed to the inactivation of telomerase.
I also benefited from David Housman, who thought a lot about multidrug resistance and how cancer cells can become resistant to chemotherapy.
When M.SssI was introduced, ds-DNA was methylated at palindromic sequence 5′…CCGG…3′ and become resistant to cleavage by HpaII and no change was observed in fluorescence intensity.
They become resistant.
But eventually tumors become resistant.
The virus may mutate and become resistant.
Drugs lose effectiveness because the microbes they fight become resistant.
If we don't use antibiotics appropriately, bacteria become resistant.
Moreover, tumours can become resistant to such agents over time.
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CEO of Professional Science Editing for Scientists @ prosciediting.com